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     moxidectin do you use this

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    IANYOUNG
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    PostSubject: moxidectin do you use this    Thu Oct 06, 2016 6:59 pm

    i use this and think this is a great wormer what do you use
    MOXIDECTIN - Product Review



    Moxidectin is regarded as the bird wormer of choice by most veterinarians.  It is effective against roundworm, hairworm and any external parasites that feed off body fluids (i.e. mites, pigeon flies).  It can be used during moulting, racing and breeding and can either be given in its concentrated form directly into the throat or alternatively diluted into the drinking water.  It is also well absorbed through the skin and can therefore be applied topically, which is convenient for small birds such as canaries and budgerigars.  The drug has a wide safety margin and birds can be fed and watered normally during its use.

    Often how products work and how they were developed is really interesting.  Moxidectin is no exception.  There is a group of chemicals called macrocyclic lactones.  Within this group are two sub-groups.  One group is the avermectins.  This includes ivermectin, which most fanciers would be familiar with.  The other group is the milbemycins.  The milbemycin group only contains two drugs, namely milbemycin and moxidectin.

    Incredibly, ivermectin was originally isolated from the fermentative broth of a fungus called Streptomyces avermitilus.  Researchers having found such a useful drug in one type of Streptomyces kept their eyes open for further species that might yield even more useful drugs.  Eventually another was found in, of all places, a golf course in northern Victoria and it was from this that moxidectin was isolated.

    Both ivermectin and moxidectin work by stimulating the release of an enzyme called GABA.  GABA is a neurotransmission inhibitor.  This means that it interferes with the normal transmission of a nervous impulse along a nerve.  In roundworms and hairworms, ivermectin does this at the junction between the central (i.e. spine) and peripheral nerves, while in insects it exerts this effect at what is called the neuromuscular junction (i.e. the gap between the end of the peripheral nerves and the muscles).  The result is that the parasite is paralyzed and dies.  Moxidectin also acts at these two sites but at two further sites as well.  Both drugs are metabolized by the liver, but moxidectin to a lesser extent, making it safer to use in birds with underlying liver problems such as Chlamydia, Salmonella or Herpes virus.  When moxidectin and ivermectin are compared, moxidectin is more potent and is also more soluble in fat (i.e. lipophilic), which means that it is more persistent in the body, exerting its effect for longer.  It is because of these reasons that moxidectin is often preferred over ivermectin.

    Although older wormers have their use at times, each has problems.  These include piperazine,  (drug resistance, decreased worm clearance), fenbendazole (causes fret marks on feathers if used during moulting) and levamisole (vomiting and worm resistance).  Moxidectin has none of these side effects.
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    PostSubject: Re: moxidectin do you use this    Thu Oct 06, 2016 7:05 pm

    yes use this product too ian if droppings test is showing any worm count
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    PostSubject: Re: moxidectin do you use this    Thu Oct 06, 2016 7:06 pm

    yes I use this have done for a number of years ,its very good
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    PostSubject: Re: moxidectin do you use this    Thu Oct 06, 2016 7:33 pm

    ive used easifen worming tablets last couple of times.....I find it very good as you can see the worms a couple of days later on the perches etc.....also kills eggs.
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    PostSubject: Re: moxidectin do you use this    Thu Oct 06, 2016 8:52 pm

    Are any of these products available over the counter or are they vet prescriptions only
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    PostSubject: Re: moxidectin do you use this    Thu Oct 06, 2016 9:17 pm

    I get mine from that pharma**** whatever its called in the homing world, just ring them up, pay over the phone and they post them out..

    I think the easifen capsules are great, the only thing I don't like is you have to give every bird a tablet, although you can get it in liquid form.

    each to their own though
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    PostSubject: Re: moxidectin do you use this    Thu Oct 06, 2016 9:29 pm

    Nice one David, thanks buddy
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    PostSubject: Re: moxidectin do you use this    Fri Oct 07, 2016 9:25 am

    Only thing with easier can't use when rearing young or when moulting
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